High-efficiency lysis of cervical cancer by allogeneic NK cells derived from umbilical cord progenitors is independent of HLA status

Down-regulation of HLA in tumor cells, low numbers and dysfunctionality of NK cells are commonly observed in patients with end-stage cervical cancer. Adoptive transfer of high numbers of cytotoxic NK cells might be a promising treatment approach in this setting. Here, we explored the cytotoxic effic...

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Detalles Bibliográficos
Autores principales: Veluchamy, John P., Heeren, A. Marijne, Spanholtz, Jan, van Eendenburg, Jaap D. H., Heideman, Daniëlle A. M., Kenter, Gemma G., Verheul, Henk M., van der Vliet, Hans J., Jordanova, Ekaterina S., de Gruijl, Tanja D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5222919/
https://www.ncbi.nlm.nih.gov/pubmed/27783105
http://dx.doi.org/10.1007/s00262-016-1919-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5222919/
https://www.ncbi.nlm.nih.gov/pubmed/27783105
http://dx.doi.org/10.1007/s00262-016-1919-1

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