A novel three-dimensional heterotypic spheroid model for the assessment of the activity of cancer immunotherapy agents

The complexity of the tumor microenvironment is difficult to mimic in vitro, particularly regarding tumor–host interactions. To enable better assessment of cancer immunotherapy agents in vitro, we developed a three-dimensional (3D) heterotypic spheroid model composed of tumor cells, fibroblasts, and...

Descripción completa

Detalles Bibliográficos
Autores principales: Herter, Sylvia, Morra, Laura, Schlenker, Ramona, Sulcova, Jitka, Fahrni, Linda, Waldhauer, Inja, Lehmann, Steffi, Reisländer, Timo, Agarkova, Irina, Kelm, Jens M., Klein, Christian, Umana, Pablo, Bacac, Marina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5222939/
https://www.ncbi.nlm.nih.gov/pubmed/27858101
http://dx.doi.org/10.1007/s00262-016-1927-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5222939/
https://www.ncbi.nlm.nih.gov/pubmed/27858101
http://dx.doi.org/10.1007/s00262-016-1927-1

Ejemplares similares