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Effects of Exendin-4 on human adipose tissue inflammation and ECM remodelling

BACKGROUND/OBJECTIVES: Subjects with type-2 diabetes are typically obese with dysfunctional adipose tissue (AT). Glucagon-like peptide-1 (GLP-1) analogues are routinely used to improve glycaemia. Although, they also aid weight loss that improves AT function, their direct effect on AT function is unc...

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Detalles Bibliográficos
Autores principales: Pastel, E, Joshi, S, Knight, B, Liversedge, N, Ward, R, Kos, K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5223133/
https://www.ncbi.nlm.nih.gov/pubmed/27941938
http://dx.doi.org/10.1038/nutd.2016.44