Covalent modification of pericardial patches for sustained rapamycin delivery inhibits venous neointimal hyperplasia

Prosthetic grafts and patches are commonly used in cardiovascular surgery, however neointimal hyperplasia remains a significant concern, especially under low flow conditions. We hypothesized that delivery of rapamycin from nanoparticles (NP) covalently attached to patches allows sustained site-speci...

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Detalles Bibliográficos
Autores principales: Bai, Hualong, Lee, Jung Seok, Chen, Elizabeth, Wang, Mo, Xing, Ying, Fahmy, Tarek M., Dardik, Alan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5223139/
https://www.ncbi.nlm.nih.gov/pubmed/28071663
http://dx.doi.org/10.1038/srep40142

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5223139/
https://www.ncbi.nlm.nih.gov/pubmed/28071663
http://dx.doi.org/10.1038/srep40142

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