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The role of the proteasome in AML

Acute myeloid leukemia (AML) is deadly hematologic malignancy. Despite a well-characterized genetic and molecular landscape, targeted therapies for AML have failed to significantly improve clinical outcomes. Over the past decade, proteasome inhibition has been demonstrated to be an effective therape...

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Detalles Bibliográficos
Autores principales: Csizmar, C M, Kim, D-H, Sachs, Z
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5223148/
https://www.ncbi.nlm.nih.gov/pubmed/27911437
http://dx.doi.org/10.1038/bcj.2016.112