Sinonasal Delivery of Resveratrol via Mucoadhesive Nanostructured Microparticles in a Nasal Polyp Mouse Model

Resveratrol (RSV) has been shown to effectively suppress chronic rhinosinusitis with nasal polyps in a mouse model; however, when locally administered to the sinonasal cavity, bolus RSV is limited by low drug bioavailability owing to its low aqueous solubility and relatively rapid clearance from the...

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Detalles Bibliográficos
Autores principales: Lee, Mingyu, Park, Chun Gwon, Huh, Beom Kang, Kim, Se-Na, Lee, Seung Ho, Khalmuratova, Roza, Park, Jong-Wan, Shin, Hyun-Woo, Choy, Young Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5223156/
https://www.ncbi.nlm.nih.gov/pubmed/28071713
http://dx.doi.org/10.1038/srep40249

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5223156/
https://www.ncbi.nlm.nih.gov/pubmed/28071713
http://dx.doi.org/10.1038/srep40249

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