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Transient anhedonia phenotype and altered circadian timing of behaviour during night-time dim light exposure in Per3(−/−) mice, but not wildtype mice

Industrialisation greatly increased human night-time exposure to artificial light, which in animal models is a known cause of depressive phenotypes. Whilst many of these phenotypes are ‘direct’ effects of light on affect, an ‘indirect’ pathway via altered sleep-wake timing has been suggested. We hav...

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Detalles Bibliográficos
Autores principales: Martynhak, Bruno Jacson, Hogben, Alexandra L., Zanos, Panos, Georgiou, Polymnia, Andreatini, Roberto, Kitchen, Ian, Archer, Simon N., von Schantz, Malcolm, Bailey, Alexis, van der Veen, Daan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5223197/
https://www.ncbi.nlm.nih.gov/pubmed/28071711
http://dx.doi.org/10.1038/srep40399