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Transient anhedonia phenotype and altered circadian timing of behaviour during night-time dim light exposure in Per3(−/−) mice, but not wildtype mice
Industrialisation greatly increased human night-time exposure to artificial light, which in animal models is a known cause of depressive phenotypes. Whilst many of these phenotypes are ‘direct’ effects of light on affect, an ‘indirect’ pathway via altered sleep-wake timing has been suggested. We hav...
Autores principales: | Martynhak, Bruno Jacson, Hogben, Alexandra L., Zanos, Panos, Georgiou, Polymnia, Andreatini, Roberto, Kitchen, Ian, Archer, Simon N., von Schantz, Malcolm, Bailey, Alexis, van der Veen, Daan R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5223197/ https://www.ncbi.nlm.nih.gov/pubmed/28071711 http://dx.doi.org/10.1038/srep40399 |
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