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Agrimonolide and Desmethylagrimonolide Induced HO-1 Expression in HepG2 Cells through Nrf2-Transduction and p38 Inactivation

Agrimonolide and desmethylagrimonolide are the main bioactive polyphenols in agrimony with well-documented antioxidant, anti-diabetic, and anti-inflammatory potential. We report here for the first time that agrimonolide and desmethylagrimonolide stimulate the expression of phase II detoxifying enzym...

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Detalles Bibliográficos
Autores principales: Chen, Lei, Teng, Hui, Zhang, Kalin Yanbo, Skalicka-Woźniak, Krystyna, Georgiev, Milen I., Xiao, Jianbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5223292/
https://www.ncbi.nlm.nih.gov/pubmed/28119605
http://dx.doi.org/10.3389/fphar.2016.00513