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The miR-34a-5p promotes the multi-chemoresistance of osteosarcoma via repression of the AGTR1 gene
BACKGROUND: Chemoresistance hinders the curative cancer chemotherapy. MicroRNAs (miRNAs) are key players in diverse biological processes including the chemoresistance of cancers. METHODS: A RNA-seq-based miR-omic analysis of osteosarcoma (OS) cells was performed to detect the levels of miR-34a-5p. B...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5223322/ https://www.ncbi.nlm.nih.gov/pubmed/28073349 http://dx.doi.org/10.1186/s12885-016-3002-x |