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The miR-34a-5p promotes the multi-chemoresistance of osteosarcoma via repression of the AGTR1 gene

BACKGROUND: Chemoresistance hinders the curative cancer chemotherapy. MicroRNAs (miRNAs) are key players in diverse biological processes including the chemoresistance of cancers. METHODS: A RNA-seq-based miR-omic analysis of osteosarcoma (OS) cells was performed to detect the levels of miR-34a-5p. B...

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Detalles Bibliográficos
Autores principales:	Pu, Youguang, Zhao, Fangfang, Li, Yinpeng, Cui, Mingda, Wang, Haiyan, Meng, Xianghui, Cai, Shanbao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5223322/ https://www.ncbi.nlm.nih.gov/pubmed/28073349 http://dx.doi.org/10.1186/s12885-016-3002-x

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