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The Irr1/Scc3 protein implicated in chromosome segregation in Saccharomyces cerevisiae has a dual nuclear-cytoplasmic localization

BACKGROUND: Correct chromosome segregation depends on the sister chromatid cohesion complex. The essential, evolutionarily conserved regulatory protein Irr1/Scc3, is responsible for the complex loading onto DNA and for its removal. We found that, unexpectedly, Irr1 is present not only in the nucleus...

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Detalles Bibliográficos
Autores principales: Kowalec, Piotr, Fronk, Jan, Kurlandzka, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5223379/
https://www.ncbi.nlm.nih.gov/pubmed/28077952
http://dx.doi.org/10.1186/s13008-016-0027-0