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Expression site of P2RY12 in residential microglial cells in astrocytomas correlates with M1 and M2 marker expression and tumor grade

The role of resident microglial cells in the pathogenesis and progression of glial tumors is still obscure mainly due to a lack of specific markers. Recently P2RY12, a P2 purinergic receptor, was introduced as a specific marker for microglial cells under normal and pathologic conditions. Here we ana...

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Detalles Bibliográficos
Autores principales: Zhu, Changbin, Kros, Johan M., van der Weiden, Marcel, Zheng, PingPin, Cheng, Caroline, Mustafa, Dana A. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5223388/
https://www.ncbi.nlm.nih.gov/pubmed/28073370
http://dx.doi.org/10.1186/s40478-016-0405-5