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Antimicrobial Peptides from Fruits and Their Potential Use as Biotechnological Tools—A Review and Outlook

Bacterial resistance is a major threat to plant crops, animals and human health, and over the years this situation has increasingly spread worldwide. Due to their many bioactive compounds, plants are promising sources of antimicrobial compounds that can potentially be used in the treatment of infect...

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Autores principales: Meneguetti, Beatriz T., Machado, Leandro dos Santos, Oshiro, Karen G. N., Nogueira, Micaella L., Carvalho, Cristiano M. E., Franco, Octávio L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5223440/
https://www.ncbi.nlm.nih.gov/pubmed/28119671
http://dx.doi.org/10.3389/fmicb.2016.02136
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author Meneguetti, Beatriz T.
Machado, Leandro dos Santos
Oshiro, Karen G. N.
Nogueira, Micaella L.
Carvalho, Cristiano M. E.
Franco, Octávio L.
author_facet Meneguetti, Beatriz T.
Machado, Leandro dos Santos
Oshiro, Karen G. N.
Nogueira, Micaella L.
Carvalho, Cristiano M. E.
Franco, Octávio L.
author_sort Meneguetti, Beatriz T.
collection PubMed
description Bacterial resistance is a major threat to plant crops, animals and human health, and over the years this situation has increasingly spread worldwide. Due to their many bioactive compounds, plants are promising sources of antimicrobial compounds that can potentially be used in the treatment of infections caused by microorganisms. As well as stem, flowers and leaves, fruits have an efficient defense mechanism against pests and pathogens, besides presenting nutritional and functional properties due to their multifunctional molecules. Among such compounds, the antimicrobial peptides (AMPs) feature different antimicrobials that are capable of disrupting the microbial membrane and of acting in binding to intra-cytoplasmic targets of microorganisms. They are therefore capable of controlling or halting the growth of microorganisms. In summary, this review describes the major classes of AMPs found in fruits, their possible use as biotechnological tools and prospects for the pharmaceutical industry and agribusiness.
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spelling pubmed-52234402017-01-24 Antimicrobial Peptides from Fruits and Their Potential Use as Biotechnological Tools—A Review and Outlook Meneguetti, Beatriz T. Machado, Leandro dos Santos Oshiro, Karen G. N. Nogueira, Micaella L. Carvalho, Cristiano M. E. Franco, Octávio L. Front Microbiol Microbiology Bacterial resistance is a major threat to plant crops, animals and human health, and over the years this situation has increasingly spread worldwide. Due to their many bioactive compounds, plants are promising sources of antimicrobial compounds that can potentially be used in the treatment of infections caused by microorganisms. As well as stem, flowers and leaves, fruits have an efficient defense mechanism against pests and pathogens, besides presenting nutritional and functional properties due to their multifunctional molecules. Among such compounds, the antimicrobial peptides (AMPs) feature different antimicrobials that are capable of disrupting the microbial membrane and of acting in binding to intra-cytoplasmic targets of microorganisms. They are therefore capable of controlling or halting the growth of microorganisms. In summary, this review describes the major classes of AMPs found in fruits, their possible use as biotechnological tools and prospects for the pharmaceutical industry and agribusiness. Frontiers Media S.A. 2017-01-10 /pmc/articles/PMC5223440/ /pubmed/28119671 http://dx.doi.org/10.3389/fmicb.2016.02136 Text en Copyright © 2017 Meneguetti, Machado, Oshiro, Nogueira, Carvalho and Franco. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Microbiology
Meneguetti, Beatriz T.
Machado, Leandro dos Santos
Oshiro, Karen G. N.
Nogueira, Micaella L.
Carvalho, Cristiano M. E.
Franco, Octávio L.
Antimicrobial Peptides from Fruits and Their Potential Use as Biotechnological Tools—A Review and Outlook
title Antimicrobial Peptides from Fruits and Their Potential Use as Biotechnological Tools—A Review and Outlook
title_full Antimicrobial Peptides from Fruits and Their Potential Use as Biotechnological Tools—A Review and Outlook
title_fullStr Antimicrobial Peptides from Fruits and Their Potential Use as Biotechnological Tools—A Review and Outlook
title_full_unstemmed Antimicrobial Peptides from Fruits and Their Potential Use as Biotechnological Tools—A Review and Outlook
title_short Antimicrobial Peptides from Fruits and Their Potential Use as Biotechnological Tools—A Review and Outlook
title_sort antimicrobial peptides from fruits and their potential use as biotechnological tools—a review and outlook
topic Microbiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5223440/
https://www.ncbi.nlm.nih.gov/pubmed/28119671
http://dx.doi.org/10.3389/fmicb.2016.02136
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