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Antimicrobial Peptides from Fruits and Their Potential Use as Biotechnological Tools—A Review and Outlook
Bacterial resistance is a major threat to plant crops, animals and human health, and over the years this situation has increasingly spread worldwide. Due to their many bioactive compounds, plants are promising sources of antimicrobial compounds that can potentially be used in the treatment of infect...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5223440/ https://www.ncbi.nlm.nih.gov/pubmed/28119671 http://dx.doi.org/10.3389/fmicb.2016.02136 |
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author | Meneguetti, Beatriz T. Machado, Leandro dos Santos Oshiro, Karen G. N. Nogueira, Micaella L. Carvalho, Cristiano M. E. Franco, Octávio L. |
author_facet | Meneguetti, Beatriz T. Machado, Leandro dos Santos Oshiro, Karen G. N. Nogueira, Micaella L. Carvalho, Cristiano M. E. Franco, Octávio L. |
author_sort | Meneguetti, Beatriz T. |
collection | PubMed |
description | Bacterial resistance is a major threat to plant crops, animals and human health, and over the years this situation has increasingly spread worldwide. Due to their many bioactive compounds, plants are promising sources of antimicrobial compounds that can potentially be used in the treatment of infections caused by microorganisms. As well as stem, flowers and leaves, fruits have an efficient defense mechanism against pests and pathogens, besides presenting nutritional and functional properties due to their multifunctional molecules. Among such compounds, the antimicrobial peptides (AMPs) feature different antimicrobials that are capable of disrupting the microbial membrane and of acting in binding to intra-cytoplasmic targets of microorganisms. They are therefore capable of controlling or halting the growth of microorganisms. In summary, this review describes the major classes of AMPs found in fruits, their possible use as biotechnological tools and prospects for the pharmaceutical industry and agribusiness. |
format | Online Article Text |
id | pubmed-5223440 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-52234402017-01-24 Antimicrobial Peptides from Fruits and Their Potential Use as Biotechnological Tools—A Review and Outlook Meneguetti, Beatriz T. Machado, Leandro dos Santos Oshiro, Karen G. N. Nogueira, Micaella L. Carvalho, Cristiano M. E. Franco, Octávio L. Front Microbiol Microbiology Bacterial resistance is a major threat to plant crops, animals and human health, and over the years this situation has increasingly spread worldwide. Due to their many bioactive compounds, plants are promising sources of antimicrobial compounds that can potentially be used in the treatment of infections caused by microorganisms. As well as stem, flowers and leaves, fruits have an efficient defense mechanism against pests and pathogens, besides presenting nutritional and functional properties due to their multifunctional molecules. Among such compounds, the antimicrobial peptides (AMPs) feature different antimicrobials that are capable of disrupting the microbial membrane and of acting in binding to intra-cytoplasmic targets of microorganisms. They are therefore capable of controlling or halting the growth of microorganisms. In summary, this review describes the major classes of AMPs found in fruits, their possible use as biotechnological tools and prospects for the pharmaceutical industry and agribusiness. Frontiers Media S.A. 2017-01-10 /pmc/articles/PMC5223440/ /pubmed/28119671 http://dx.doi.org/10.3389/fmicb.2016.02136 Text en Copyright © 2017 Meneguetti, Machado, Oshiro, Nogueira, Carvalho and Franco. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Microbiology Meneguetti, Beatriz T. Machado, Leandro dos Santos Oshiro, Karen G. N. Nogueira, Micaella L. Carvalho, Cristiano M. E. Franco, Octávio L. Antimicrobial Peptides from Fruits and Their Potential Use as Biotechnological Tools—A Review and Outlook |
title | Antimicrobial Peptides from Fruits and Their Potential Use as Biotechnological Tools—A Review and Outlook |
title_full | Antimicrobial Peptides from Fruits and Their Potential Use as Biotechnological Tools—A Review and Outlook |
title_fullStr | Antimicrobial Peptides from Fruits and Their Potential Use as Biotechnological Tools—A Review and Outlook |
title_full_unstemmed | Antimicrobial Peptides from Fruits and Their Potential Use as Biotechnological Tools—A Review and Outlook |
title_short | Antimicrobial Peptides from Fruits and Their Potential Use as Biotechnological Tools—A Review and Outlook |
title_sort | antimicrobial peptides from fruits and their potential use as biotechnological tools—a review and outlook |
topic | Microbiology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5223440/ https://www.ncbi.nlm.nih.gov/pubmed/28119671 http://dx.doi.org/10.3389/fmicb.2016.02136 |
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