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Inferring Heterozygosity from Ancient and Low Coverage Genomes

While genetic diversity can be quantified accurately from high coverage sequencing data, it is often desirable to obtain such estimates from data with low coverage, either to save costs or because of low DNA quality, as is observed for ancient samples. Here, we introduce a method to accurately infer...

תיאור מלא

מידע ביבליוגרפי
Autores principales: Kousathanas, Athanasios, Leuenberger, Christoph, Link, Vivian, Sell, Christian, Burger, Joachim, Wegmann, Daniel
פורמט: Online Artículo Texto
שפה:English
יצא לאור: Genetics Society of America 2017
נושאים:
גישה מקוונת:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5223511/
https://www.ncbi.nlm.nih.gov/pubmed/27821432
http://dx.doi.org/10.1534/genetics.116.189985