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Controlling the Rate of GWAS False Discoveries

With the rise of both the number and the complexity of traits of interest, control of the false discovery rate (FDR) in genetic association studies has become an increasingly appealing and accepted target for multiple comparison adjustment. While a number of robust FDR-controlling strategies exist,...

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Detalles Bibliográficos
Autores principales: Brzyski, Damian, Peterson, Christine B., Sobczyk, Piotr, Candès, Emmanuel J., Bogdan, Malgorzata, Sabatti, Chiara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5223524/
https://www.ncbi.nlm.nih.gov/pubmed/27784720
http://dx.doi.org/10.1534/genetics.116.193987