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Activating the nuclear piston mechanism of 3D migration in tumor cells

Primary human fibroblasts have the remarkable ability to use their nucleus like a piston, switching from low- to high-pressure protrusions in response to the surrounding three-dimensional (3D) matrix. Although migrating tumor cells can also change how they migrate in response to the 3D matrix, it is...

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Detalles Bibliográficos
Autores principales: Petrie, Ryan J., Harlin, Heather M., Korsak, Lulu I T., Yamada, Kenneth M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5223602/
https://www.ncbi.nlm.nih.gov/pubmed/27998990
http://dx.doi.org/10.1083/jcb.201605097