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Two distinct membrane potential–dependent steps drive mitochondrial matrix protein translocation

Two driving forces energize precursor translocation across the inner mitochondrial membrane. Although the membrane potential (Δψ) is considered to drive translocation of positively charged presequences through the TIM23 complex (presequence translocase), the activity of the Hsp70-powered import moto...

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Detalles Bibliográficos
Autores principales: Schendzielorz, Alexander Benjamin, Schulz, Christian, Lytovchenko, Oleksandr, Clancy, Anne, Guiard, Bernard, Ieva, Raffaele, van der Laan, Martin, Rehling, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5223606/
https://www.ncbi.nlm.nih.gov/pubmed/28011846
http://dx.doi.org/10.1083/jcb.201607066