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Two distinct membrane potential–dependent steps drive mitochondrial matrix protein translocation
Two driving forces energize precursor translocation across the inner mitochondrial membrane. Although the membrane potential (Δψ) is considered to drive translocation of positively charged presequences through the TIM23 complex (presequence translocase), the activity of the Hsp70-powered import moto...
Autores principales: | Schendzielorz, Alexander Benjamin, Schulz, Christian, Lytovchenko, Oleksandr, Clancy, Anne, Guiard, Bernard, Ieva, Raffaele, van der Laan, Martin, Rehling, Peter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5223606/ https://www.ncbi.nlm.nih.gov/pubmed/28011846 http://dx.doi.org/10.1083/jcb.201607066 |
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