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Growth differentiation factor 15 is a myomitokine governing systemic energy homeostasis

Reduced mitochondrial electron transport chain activity promotes longevity and improves energy homeostasis via cell-autonomous and –non-autonomous factors in multiple model systems. This mitohormetic effect is thought to involve the mitochondrial unfolded protein response (UPR(mt)), an adaptive stre...

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Detalles Bibliográficos
Autores principales: Chung, Hyo Kyun, Ryu, Dongryeol, Kim, Koon Soon, Chang, Joon Young, Kim, Yong Kyung, Yi, Hyon-Seung, Kang, Seul Gi, Choi, Min Jeong, Lee, Seong Eun, Jung, Saet-Byel, Ryu, Min Jeong, Kim, Soung Jung, Kweon, Gi Ryang, Kim, Hail, Hwang, Jung Hwan, Lee, Chul-Ho, Lee, Se-Jin, Wall, Christopher E., Downes, Michael, Evans, Ronald M., Auwerx, Johan, Shong, Minho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5223607/
https://www.ncbi.nlm.nih.gov/pubmed/27986797
http://dx.doi.org/10.1083/jcb.201607110