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Growth differentiation factor 15 is a myomitokine governing systemic energy homeostasis
Reduced mitochondrial electron transport chain activity promotes longevity and improves energy homeostasis via cell-autonomous and –non-autonomous factors in multiple model systems. This mitohormetic effect is thought to involve the mitochondrial unfolded protein response (UPR(mt)), an adaptive stre...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5223607/ https://www.ncbi.nlm.nih.gov/pubmed/27986797 http://dx.doi.org/10.1083/jcb.201607110 |