Regulation of clathrin-mediated endocytosis by hierarchical allosteric activation of AP2

The critical initiation phase of clathrin-mediated endocytosis (CME) determines where and when endocytosis occurs. Heterotetrameric adaptor protein 2 (AP2) complexes, which initiate clathrin-coated pit (CCP) assembly, are activated by conformational changes in response to phosphatidylinositol-4,5-bi...

Descripción completa

Detalles Bibliográficos
Autores principales: Kadlecova, Zuzana, Spielman, Stephanie J., Loerke, Dinah, Mohanakrishnan, Aparna, Reed, Dana Kim, Schmid, Sandra L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5223608/
https://www.ncbi.nlm.nih.gov/pubmed/28003333
http://dx.doi.org/10.1083/jcb.201608071

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5223608/
https://www.ncbi.nlm.nih.gov/pubmed/28003333
http://dx.doi.org/10.1083/jcb.201608071

Ejemplares similares