The palmitoyltransferase Approximated promotes growth via the Hippo pathway by palmitoylation of Fat

The large protocadherin Fat functions to promote Hippo pathway activity in restricting tissue growth. Loss of Fat leads to accumulation of the atypical myosin Dachs at the apical junctional region, which in turn promotes growth by inhibiting Warts. We previously identified Approximated (App), a DHHC...

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Detalles Bibliográficos
Autores principales: Matakatsu, Hitoshi, Blair, Seth S., Fehon, Richard G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5223609/
https://www.ncbi.nlm.nih.gov/pubmed/28031421
http://dx.doi.org/10.1083/jcb.201609094

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5223609/
https://www.ncbi.nlm.nih.gov/pubmed/28031421
http://dx.doi.org/10.1083/jcb.201609094

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