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The palmitoyltransferase Approximated promotes growth via the Hippo pathway by palmitoylation of Fat
The large protocadherin Fat functions to promote Hippo pathway activity in restricting tissue growth. Loss of Fat leads to accumulation of the atypical myosin Dachs at the apical junctional region, which in turn promotes growth by inhibiting Warts. We previously identified Approximated (App), a DHHC...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5223609/ https://www.ncbi.nlm.nih.gov/pubmed/28031421 http://dx.doi.org/10.1083/jcb.201609094 |