Endomorphin-2 Inhibition of Substance P Signaling within Lamina I of the Spinal Cord Is Impaired in Diabetic Neuropathic Pain Rats

Opiate analgesia in the spinal cord is impaired in diabetic neuropathic pain (DNP), but until now the reason is unknown. We hypothesized that it resulted from a decreased inhibition of substance P (SP) signaling within the dorsal horn of the spinal cord. To investigate this possibility, we evaluated...

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Detalles Bibliográficos
Autores principales: Wan, Fa-Ping, Bai, Yang, Kou, Zhen-Zhen, Zhang, Ting, Li, Hui, Wang, Ya-Yun, Li, Yun-Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5223733/
https://www.ncbi.nlm.nih.gov/pubmed/28119567
http://dx.doi.org/10.3389/fnmol.2016.00167

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5223733/
https://www.ncbi.nlm.nih.gov/pubmed/28119567
http://dx.doi.org/10.3389/fnmol.2016.00167

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