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Thermotoga maritima NusG: domain interaction mediates autoinhibition and thermostability

NusG, the only universally conserved transcription factor, comprises an N- and a C-terminal domain (NTD, CTD) that are flexibly connected and move independently in Escherichia coli and other organisms. In NusG from the hyperthermophilic bacterium Thermotoga maritima (tmNusG), however, NTD and CTD in...

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Detalles Bibliográficos
Autores principales: Drögemüller, Johanna, Schneider, Christin, Schweimer, Kristian, Strauß, Martin, Wöhrl, Birgitta M., Rösch, Paul, Knauer, Stefan H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5224480/
https://www.ncbi.nlm.nih.gov/pubmed/27899597
http://dx.doi.org/10.1093/nar/gkw1111