An mRNA-specific tRNA(i) carrier eIF2A plays a pivotal role in cell proliferation under stress conditions: stress-resistant translation of c-Src mRNA is mediated by eIF2A

c-Src, a non-receptor protein tyrosine kinase, activates NF-κB and STAT3, which in turn triggers the transcription of anti-apoptosis- and cell cycle-related genes. c-Src protein regulates cell proliferation, cell motility and programmed cell death. And the elevated level of activated c-Src protein i...

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Detalles Bibliográficos
Autores principales: Kwon, Oh Sung, An, Sihyeon, Kim, Eunah, Yu, Jinbae, Hong, Ka Young, Lee, Jae Seung, Jang, Sung Key
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5224483/
https://www.ncbi.nlm.nih.gov/pubmed/27899592
http://dx.doi.org/10.1093/nar/gkw1117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5224483/
https://www.ncbi.nlm.nih.gov/pubmed/27899592
http://dx.doi.org/10.1093/nar/gkw1117

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