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Structures of human SRP72 complexes provide insights into SRP RNA remodeling and ribosome interaction

Co-translational protein targeting and membrane protein insertion is a fundamental process and depends on the signal recognition particle (SRP). In mammals, SRP is composed of the SRP RNA crucial for SRP assembly and function and six proteins. The two largest proteins SRP68 and SRP72 form a heterodi...

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Detalles Bibliográficos
Autores principales: Becker, Matthias M. M., Lapouge, Karine, Segnitz, Bernd, Wild, Klemens, Sinning, Irmgard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5224484/
https://www.ncbi.nlm.nih.gov/pubmed/27899666
http://dx.doi.org/10.1093/nar/gkw1124