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Regulated complex assembly safeguards the fidelity of Sleeping Beauty transposition

The functional relevance of the inverted repeat structure (IR/DR) in a subgroup of the Tc1/mariner superfamily of transposons has been enigmatic. In contrast to mariner transposition, where a topological filter suppresses single-ended reactions, the IR/DR orchestrates a regulatory mechanism to enfor...

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Detalles Bibliográficos
Autores principales: Wang, Yongming, Pryputniewicz-Dobrinska, Diana, Nagy, Enikö Éva, Kaufman, Christopher D., Singh, Manvendra, Yant, Steve, Wang, Jichang, Dalda, Anna, Kay, Mark A., Ivics, Zoltán, Izsvák, Zsuzsanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5224488/
https://www.ncbi.nlm.nih.gov/pubmed/27913727
http://dx.doi.org/10.1093/nar/gkw1164