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The bromodomain protein BRD4 regulates splicing during heat shock

The cellular response to heat stress is an ancient and evolutionarily highly conserved defence mechanism characterised by the transcriptional up-regulation of cyto-protective genes and a partial inhibition of splicing. These features closely resemble the proteotoxic stress response during tumor deve...

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Detalles Bibliográficos
Autores principales: Hussong, Michelle, Kaehler, Christian, Kerick, Martin, Grimm, Christina, Franz, Alexandra, Timmermann, Bernd, Welzel, Franziska, Isensee, Jörg, Hucho, Tim, Krobitsch, Sylvia, Schweiger, Michal R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5224492/
https://www.ncbi.nlm.nih.gov/pubmed/27536004
http://dx.doi.org/10.1093/nar/gkw729