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The bromodomain protein BRD4 regulates splicing during heat shock
The cellular response to heat stress is an ancient and evolutionarily highly conserved defence mechanism characterised by the transcriptional up-regulation of cyto-protective genes and a partial inhibition of splicing. These features closely resemble the proteotoxic stress response during tumor deve...
Autores principales: | Hussong, Michelle, Kaehler, Christian, Kerick, Martin, Grimm, Christina, Franz, Alexandra, Timmermann, Bernd, Welzel, Franziska, Isensee, Jörg, Hucho, Tim, Krobitsch, Sylvia, Schweiger, Michal R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5224492/ https://www.ncbi.nlm.nih.gov/pubmed/27536004 http://dx.doi.org/10.1093/nar/gkw729 |
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