The dual role of LSD1 and HDAC3 in STAT5-dependent transcription is determined by protein interactions, binding affinities, motifs and genomic positions

STAT5 interacts with other factors to control transcription, and the mechanism of regulation is of interest as constitutive active STAT5 has been reported in malignancies. Here, LSD1 and HDAC3 were identified as novel STAT5a interacting partners in pro-B cells. Characterization of STAT5a, LSD1 and H...

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Detalles Bibliográficos
Autores principales: Nanou, Aikaterini, Toumpeki, Chrisavgi, Lavigne, Matthieu D., Lazou, Vassiliki, Demmers, Jeroen, Paparountas, Triantafillos, Thanos, Dimitris, Katsantoni, Eleni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5224505/
https://www.ncbi.nlm.nih.gov/pubmed/27651463
http://dx.doi.org/10.1093/nar/gkw832

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5224505/
https://www.ncbi.nlm.nih.gov/pubmed/27651463
http://dx.doi.org/10.1093/nar/gkw832

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