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H3K9me3 demethylase Kdm4d facilitates the formation of pre-initiative complex and regulates DNA replication

DNA replication is tightly regulated to occur once and only once per cell cycle. How chromatin, the physiological substrate of DNA replication machinery, regulates DNA replication remains largely unknown. Here we show that histone H3 lysine 9 demethylase Kdm4d regulates DNA replication in eukaryotic...

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Detalles Bibliográficos
Autores principales: Wu, Rentian, Wang, Zhiquan, Zhang, Honglian, Gan, Haiyun, Zhang, Zhiguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5224507/
https://www.ncbi.nlm.nih.gov/pubmed/27679476
http://dx.doi.org/10.1093/nar/gkw848