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Activation of cGAS-dependent antiviral responses by DNA intercalating agents

Acridine dyes, including proflavine and acriflavine, were commonly used as antiseptics before the advent of penicillins in the mid-1940s. While their mode of action on pathogens was originally attributed to their DNA intercalating activity, work in the early 1970s suggested involvement of the host i...

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Detalles Bibliográficos
Autores principales: Pépin, Geneviève, Nejad, Charlotte, Thomas, Belinda J., Ferrand, Jonathan, McArthur, Kate, Bardin, Philip G., Williams, Bryan R.G., Gantier, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5224509/
https://www.ncbi.nlm.nih.gov/pubmed/27694309
http://dx.doi.org/10.1093/nar/gkw878