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Esc2 promotes Mus81 complex-activity via its SUMO-like and DNA binding domains

Replication across damaged DNA templates is accompanied by transient formation of sister chromatid junctions (SCJs). Cells lacking Esc2, an adaptor protein containing no known enzymatic domains, are defective in the metabolism of these SCJs. However, how Esc2 is involved in the metabolism of SCJs re...

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Detalles Bibliográficos
Autores principales: Sebesta, Marek, Urulangodi, Madhusoodanan, Stefanovie, Barbora, Szakal, Barnabas, Pacesa, Martin, Lisby, Michael, Branzei, Dana, Krejci, Lumir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5224511/
https://www.ncbi.nlm.nih.gov/pubmed/27694623
http://dx.doi.org/10.1093/nar/gkw882