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A ribosome profiling study of mRNA cleavage by the endonuclease RelE

Implicated in persistence and stress response pathways in bacteria, RelE shuts down protein synthesis by cleaving mRNA within the ribosomal A site. Structural and biochemical studies have shown that RelE cuts with some sequence specificity, which we further characterize here, and that it shows no ac...

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Detalles Bibliográficos
Autores principales: Hwang, Jae-Yeon, Buskirk, Allen R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5224514/
https://www.ncbi.nlm.nih.gov/pubmed/27924019
http://dx.doi.org/10.1093/nar/gkw944