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A ribosome profiling study of mRNA cleavage by the endonuclease RelE
Implicated in persistence and stress response pathways in bacteria, RelE shuts down protein synthesis by cleaving mRNA within the ribosomal A site. Structural and biochemical studies have shown that RelE cuts with some sequence specificity, which we further characterize here, and that it shows no ac...
Autores principales: | Hwang, Jae-Yeon, Buskirk, Allen R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5224514/ https://www.ncbi.nlm.nih.gov/pubmed/27924019 http://dx.doi.org/10.1093/nar/gkw944 |
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