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Rap1A promotes ovarian cancer metastasis via activation of ERK/p38 and notch signaling

As one of the Ras‐associated proteins, Rap1A has been linked to cancer initiation and development. However, the precise function of Rap1A in ovarian cancer is still not understood. Here, we show that Rap1A promotes ovarian cancer tumorigenesis and metastasis via stimulating cell proliferation, migra...

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Detalles Bibliográficos
Autores principales: Lu, Lili, Wang, Jingshu, Wu, Yougen, Wan, Ping, Yang, Gong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5224839/
https://www.ncbi.nlm.nih.gov/pubmed/27925454
http://dx.doi.org/10.1002/cam4.946