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The role of FilGAP, a Rac‐specific Rho‐GTPase‐activating protein, in tumor progression and behavior of astrocytomas
FilGAP, a Rac‐specific Rho‐GTPase‐activating protein (GAP), acts as a mediator of Rho/ROCK‐dependent amoeboid movement, and its knockdown results in Rac‐driven mesenchymal morphology. Herein, we focused on the possible roles of FilGAP expression in astrocytomas. In clinical samples, FilGAP expressio...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5224849/ https://www.ncbi.nlm.nih.gov/pubmed/27790861 http://dx.doi.org/10.1002/cam4.937 |