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The role of FilGAP, a Rac‐specific Rho‐GTPase‐activating protein, in tumor progression and behavior of astrocytomas

FilGAP, a Rac‐specific Rho‐GTPase‐activating protein (GAP), acts as a mediator of Rho/ROCK‐dependent amoeboid movement, and its knockdown results in Rac‐driven mesenchymal morphology. Herein, we focused on the possible roles of FilGAP expression in astrocytomas. In clinical samples, FilGAP expressio...

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Detalles Bibliográficos
Autores principales:	Hara, Atsuko, Hashimura, Miki, Tsutsumi, Koji, Akiya, Masashi, Inukai, Madoka, Ohta, Yasutaka, Saegusa, Makoto
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2016
Materias:	Clinical Cancer Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5224849/ https://www.ncbi.nlm.nih.gov/pubmed/27790861 http://dx.doi.org/10.1002/cam4.937

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