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EMC1-dependent stabilization drives membrane penetration of a partially destabilized non-enveloped virus

Destabilization of a non-enveloped virus generates a membrane transport-competent viral particle. Here we probe polyomavirus SV40 endoplasmic reticulum (ER)-to-cytosol membrane transport, a decisive infection step where destabilization initiates this non-enveloped virus for membrane penetration. We...

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Detalles Bibliográficos
Autores principales: Bagchi, Parikshit, Inoue, Takamasa, Tsai, Billy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5224922/
https://www.ncbi.nlm.nih.gov/pubmed/28012275
http://dx.doi.org/10.7554/eLife.21470