Cargando…
EMC1-dependent stabilization drives membrane penetration of a partially destabilized non-enveloped virus
Destabilization of a non-enveloped virus generates a membrane transport-competent viral particle. Here we probe polyomavirus SV40 endoplasmic reticulum (ER)-to-cytosol membrane transport, a decisive infection step where destabilization initiates this non-enveloped virus for membrane penetration. We...
Autores principales: | Bagchi, Parikshit, Inoue, Takamasa, Tsai, Billy |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5224922/ https://www.ncbi.nlm.nih.gov/pubmed/28012275 http://dx.doi.org/10.7554/eLife.21470 |
Ejemplares similares
-
A Non-enveloped Virus Hijacks Host Disaggregation Machinery to Translocate across the Endoplasmic Reticulum Membrane
por: Ravindran, Madhu Sudhan, et al.
Publicado: (2015) -
Regulated Erlin-dependent release of the B12 transmembrane J-protein promotes ER membrane penetration of a non-enveloped virus
por: Inoue, Takamasa, et al.
Publicado: (2017) -
Selective EMC subunits act as molecular tethers of intracellular organelles exploited during viral entry
por: Bagchi, Parikshit, et al.
Publicado: (2020) -
A specific EMC subunit supports Dengue virus infection by promoting virus membrane fusion essential for cytosolic genome delivery
por: Bagchi, Parikshit, et al.
Publicado: (2022) -
Structural and mechanistic basis of the EMC-dependent biogenesis of distinct transmembrane clients
por: Miller-Vedam, Lakshmi E, et al.
Publicado: (2020)