Rsp5/Nedd4 is the major ubiquitin ligase that targets cytosolic misfolded proteins upon heat-stress

The heat-shock response is a complex cellular program that induces major changes in protein translation, folding and degradation to alleviate toxicity caused by protein misfolding. While heat-shock has been widely used to study proteostasis, it remained unclear how misfolded proteins are targeted fo...

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Detalles Bibliográficos
Autores principales: Fang, Nancy N., Chan, Gerard T., Zhu, Mang, Comyn, Sophie A., Persaud, Avinash, Deshaies, Raymond J., Rotin, Daniela, Gsponer, Joerg, Mayor, Thibault
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5224936/
https://www.ncbi.nlm.nih.gov/pubmed/25344756
http://dx.doi.org/10.1038/ncb3054

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5224936/
https://www.ncbi.nlm.nih.gov/pubmed/25344756
http://dx.doi.org/10.1038/ncb3054

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