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Drosophila Clock Is Required in Brain Pacemaker Neurons to Prevent Premature Locomotor Aging Independently of Its Circadian Function

Circadian clocks control many self-sustained rhythms in physiology and behavior with approximately 24-hour periodicity. In many organisms, oxidative stress and aging negatively impact the circadian system and sleep. Conversely, loss of the clock decreases resistance to oxidative stress, and may redu...

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Detalles Bibliográficos
Autores principales: Vaccaro, Alexandra, Issa, Abdul-Raouf, Seugnet, Laurent, Birman, Serge, Klarsfeld, André
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5224980/
https://www.ncbi.nlm.nih.gov/pubmed/28072817
http://dx.doi.org/10.1371/journal.pgen.1006507