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Increased PD-1 Expression and Altered T Cell Repertoire Diversity Predict Mortality in Patients with Septic Shock: A Preliminary Study

Sepsis causes impairment of innate and adaptive immunity by multiple mechanisms, including depletion of immune effector cells and T cell exhaustion. Although lymphocyte dysfunction is associated with increased mortality and potential reactivation of latent viral infection in patients with septic sho...

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Detalles Bibliográficos
Autores principales: Tomino, Atsutoshi, Tsuda, Masanobu, Aoki, Ruri, Kajita, Yuka, Hashiba, Masamitsu, Terajima, Tsuguaki, Kano, Hideki, Takeyama, Naoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5225000/
https://www.ncbi.nlm.nih.gov/pubmed/28072859
http://dx.doi.org/10.1371/journal.pone.0169653