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Increased PD-1 Expression and Altered T Cell Repertoire Diversity Predict Mortality in Patients with Septic Shock: A Preliminary Study
Sepsis causes impairment of innate and adaptive immunity by multiple mechanisms, including depletion of immune effector cells and T cell exhaustion. Although lymphocyte dysfunction is associated with increased mortality and potential reactivation of latent viral infection in patients with septic sho...
Autores principales: | Tomino, Atsutoshi, Tsuda, Masanobu, Aoki, Ruri, Kajita, Yuka, Hashiba, Masamitsu, Terajima, Tsuguaki, Kano, Hideki, Takeyama, Naoshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5225000/ https://www.ncbi.nlm.nih.gov/pubmed/28072859 http://dx.doi.org/10.1371/journal.pone.0169653 |
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