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Comprehensive N-Glycan Profiling of Cetuximab Biosimilar Candidate by NP-HPLC and MALDI-MS

Monitoring glycosylation of the mAbs have been emphasized and routinely characterized in biopharmaceutical industries because the carbohydrate components are closely related to the safety, efficacy, and consistency of the antibodies. In this study, the comprehensive glycan profiling of a biosimilar...

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Detalles Bibliográficos
Autores principales: Liu, Sheng, Gao, Wenjie, Wang, Yao, He, Zhenyu, Feng, Xiaojun, Liu, Bi-Feng, Liu, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5225015/
https://www.ncbi.nlm.nih.gov/pubmed/28072827
http://dx.doi.org/10.1371/journal.pone.0170013