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Mutation of the Ser18 phosphorylation site on the sole Saccharomyces cerevisiae UCS protein, She4, can compromise high-temperature survival

Folding of the myosin head often requires the joint actions of Hsp90 and a dedicated UNC45, Cro1, She4 (UCS) domain-containing cochaperone protein. Relatively weak sequence conservation exists between the single UCS protein of simple eukaryotes (She4 in budding yeast) and the two UCS proteins of hig...

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Detalles Bibliográficos
Autores principales: Gomez-Escalante, Susana, Piper, Peter W., Millson, Stefan H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5225067/
https://www.ncbi.nlm.nih.gov/pubmed/27888470
http://dx.doi.org/10.1007/s12192-016-0750-0