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Anti-GPC3-CAR T Cells Suppress the Growth of Tumor Cells in Patient-Derived Xenografts of Hepatocellular Carcinoma

BACKGROUND: The lack of a general clinic-relevant model for human cancer is a major impediment to the acceleration of novel therapeutic approaches for clinical use. We propose to establish and characterize primary human hepatocellular carcinoma (HCC) xenografts that can be used to evaluate the cytot...

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Detalles Bibliográficos
Autores principales: Jiang, Zhiwu, Jiang, Xiaofeng, Chen, Suimin, Lai, Yunxin, Wei, Xinru, Li, Baiheng, Lin, Simiao, Wang, Suna, Wu, Qiting, Liang, Qiubin, Liu, Qifa, Peng, Muyun, Yu, Fenglei, Weng, Jianyu, Du, Xin, Pei, Duanqing, Liu, Pentao, Yao, Yao, Xue, Ping, Li, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5225101/
https://www.ncbi.nlm.nih.gov/pubmed/28123387
http://dx.doi.org/10.3389/fimmu.2016.00690