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Fingerprinting of neurotoxic compounds using a mouse embryonic stem cell dual luminescence reporter assay

Identification of neurotoxic drugs and environmental chemicals is an important challenge. However, only few tools to address this topic are available. The aim of this study was to develop a neurotoxicity/developmental neurotoxicity (DNT) test system, using the pluripotent mouse embryonic stem cell l...

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Detalles Bibliográficos
Autores principales: Colaianna, Marilena, Ilmjärv, Sten, Peterson, Hedi, Kern, Ilse, Julien, Stephanie, Baquié, Mathurin, Pallocca, Giorgia, Bosgra, Sieto, Sachinidis, Agapios, Hengstler, Jan G., Leist, Marcel, Krause, Karl-Heinz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5225183/
https://www.ncbi.nlm.nih.gov/pubmed/27015953
http://dx.doi.org/10.1007/s00204-016-1690-2