Cargando…
Fingerprinting of neurotoxic compounds using a mouse embryonic stem cell dual luminescence reporter assay
Identification of neurotoxic drugs and environmental chemicals is an important challenge. However, only few tools to address this topic are available. The aim of this study was to develop a neurotoxicity/developmental neurotoxicity (DNT) test system, using the pluripotent mouse embryonic stem cell l...
Autores principales: | Colaianna, Marilena, Ilmjärv, Sten, Peterson, Hedi, Kern, Ilse, Julien, Stephanie, Baquié, Mathurin, Pallocca, Giorgia, Bosgra, Sieto, Sachinidis, Agapios, Hengstler, Jan G., Leist, Marcel, Krause, Karl-Heinz |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5225183/ https://www.ncbi.nlm.nih.gov/pubmed/27015953 http://dx.doi.org/10.1007/s00204-016-1690-2 |
Ejemplares similares
-
Profiling of drugs and environmental chemicals for functional impairment of neural crest migration in a novel stem cell-based test battery
por: Zimmer, B., et al.
Publicado: (2014) -
Identification of transcriptome signatures and biomarkers specific for potential developmental toxicants inhibiting human neural crest cell migration
por: Pallocca, Giorgia, et al.
Publicado: (2015) -
Impairment of human neural crest cell migration by prolonged exposure to interferon-beta
por: Pallocca, Giorgia, et al.
Publicado: (2017) -
Cell death mechanisms of the anti-cancer drug etoposide on human cardiomyocytes isolated from pluripotent stem cells
por: Nemade, Harshal, et al.
Publicado: (2018) -
Functional cardiotoxicity assessment of cosmetic compounds using human-induced pluripotent stem cell-derived cardiomyocytes
por: Chaudhari, Umesh, et al.
Publicado: (2017)